Preparation and application background and overview of 2-aminoethyl diphenylborate
2-Aminoethyl diphenylborate, also known as 2-aminoethyl diphenylborate, is an organic intermediate that can be prepared by the reaction of bromobenzene, ethanolamine and trimethyl borate. There are reports in the literature that it can be used to prepare saxitoxin and its derivatives.
Preparation and application of diphenylboronic acid-2-aminoethyl ester
Stir a mixture of magnesium tuner (11 mmol, 267.3 mg, 1.1 equiv) and small crystals of iodine in THF (5 mL) under an argon atmosphere until decolorization is complete at 40 °C for 30 min. To the mixture was added dropwise a mixture of bromobenzene (1.05 mL, 10 mmol) and B(OMe)3 (5 mmol, 0.56 mL, 0.5 equiv) in THF (5 mL). Keep the reaction at 40°C for another two hours. Cool the reaction mixture to room temperature, add 5% HCl aqueous solution (5.75 mL) to the mixture to achieve hydrolysis, stir the resulting mixture for 30 min, extract the reaction mixture with EtOAc (3 x 10 mL), wash the organic layer with anhydrous magnesium sulfate The mixture was dried and concentrated under reduced pressure. The crude product was dissolved in EtOAc (1.2 mL). 2-ethanolamine (10 mmol, 0.60 mL, 1 eq.) was added to the mixture. The reaction mixture was stirred overnight. The mixture was washed with water and brine. The mixture was extracted with EtOAc (2 x 3 mL) and concentrated in vacuo to give crude product. The crude product is recrystallized from ethanol, acetone or chloroform to give the product.
Preparation and application of diphenylboronic acid-2-aminoethyl ester
CN201510708996.6 discloses an interior wall coating, which is made of the following raw materials in parts by weight: 5-10 parts of titanium dioxide, 5-10 parts of white carbon black, 15-20 parts of epoxy latex, 4-tert. 5.8-12.7 parts of butylcyclohexanol, 3.5-7.4 parts of 2-aminoethyl diphenylborate, 3.5-6.5 parts of phenylethyl biphenol polyoxyethylene ether, 2.5-4.7 parts of lily aldehyde and 1.5-1.5 parts of monoethanolamine 2.7 servings. Compared with the existing products, the present invention adds epoxy latex and 4-tert-butylcyclohexanol. After the two are mixed, the content of volatile organic matter is less, the environmental pollution is less, the energy saving and emission reduction, low carbon and environmental protection; diphenyl After mixing 2-aminoethyl borate, phenylethyl biphenol polyoxyethylene ether and lily aldehyde, the mildew resistance and scrub resistance of latex paint are improved, and the service life of the latex paint finished product is improved. It can be widely used in Wall painting.
References
[1]Dine chloropyridinium T , Rouden J H , mica Jérme Blanchet. Borinic acid Catalysed Peptide Synthesis[J]. Chemical Communications, 2015, 51(89).
[2] Organic Letters, 22(21), 8697-8701; 2020
[3] CN201510708996.6 An interior wall coating
