Overview of the preparation of 2,2′-dipyridylamine
2,2′-Dipyridylamine is an organic synthesis intermediate and pharmaceutical intermediate. It is mainly used in laboratory organic synthesis processes and chemical and pharmaceutical synthesis processes. There are literature reports that it can be used to prepare palladium nanoparticles and palladium nanoparticles. particle.
Preparation of 2,2′-dipyridylamine
Tri-tert-butylphosphine, palladium acetate and sodium tert-butoxide were added to a solution of 2-aminopyridine and 2-bromopyridine in degassed toluene, and the mixture was heated under reflux for 2 hours. The reaction mixture was cooled to room temperature, diluted with toluene and filtered through Celite. The filtrate was diluted with water and extracted with toluene, and the organic phase of bromomethylbenzeneborate pinacol ester was combined and evaporated under vacuum. The residue was filtered through silica gel and repurified to give 2,2′-dipyridylamine.
Preparation and application of 2,2′-dipyridylamine
CN200810032523.9 discloses a catalyst for palladium sodium carbonate nanoparticles and a preparation method thereof. The catalyst includes polyethylene glycol, functionalized polyethylene glycol and stable palladium nanoparticles. The catalyst preparation steps are: 1) reacting polyethylene glycol with methylsulfonyl chloride to obtain polyethylene glycol methanesulfonate; 2) reacting 2,2′-dipyridylamine with polyethylene glycol methanesulfonate, Obtain 2,2′-dipyridylamine functionalized polyethylene glycol; 3) In the toluene solution of 2,2′-dipyridylamine functionalized polyethylene glycol, add palladium acetate and polyethylene glycol, and heat and reduce , drain the solvent to obtain a stable palladium nanoparticle catalyst. The prepared palladium nanocatalyst can be used in the selective oxidation reaction of various alcohols. Compared with other catalysts, it has the advantages of high activity, good selectivity and easy catalyst separation.
CN200810032615.7 discloses a new type of functionalized ionic liquid based on bidentate nitrogen ligands and a synthesis method of this type of ionic liquid, which belongs to the field of new chemical materials and their preparation technology. The synthesis steps are as follows: using terminal positions Chlorinated acid chloride and 2,2′-dipyridylamine are used as raw materials, and triethylamine is used as an acid binding agent to generate an amide intermediate containing a bidentate nitrogen ligand. This intermediate is then mixed with 1-alkyl-2- Methyl (or hydrogen) imidazole reacts to generate imidazole cations containing bidentate nitrogen ligands, and the anions are chlorine functional ionic liquids. Finally, anions are exchanged with various inorganic salts to obtain the required anions and contain 2,2′- Ionic liquids functionalized with bipyridylamine bidentate nitrogen ligands. The present invention combines a bidentate nitrogen ligand with an ionic liquid for the first time, which provides a basis for the research and development of new functional ionic liquids. It has a wide range of applications, simple operation and high yield, and provides a basis for the development and development of new functional ionic liquids in the future. The application provides a new path.
